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About Zhihe Bio

Chinese Ceramide Fountainhead

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Message from the President

ceo

The name "Zhihe" is derived from the ancient Chinese literature, meaning "to harmonize and connect with the world." This reflects our commitment to diligent exploration, continuously expanding our knowledge, and reaching out globally.

 

Since its establishment, Zhihe has adhered to the philosophy of continuous innovation and entrepreneurship, persistently exploring the unknown realms of biotechnology. We have achieved numerous significant milestones and made substantial contributions to society.

 

Looking ahead, Zhihe remains dedicated to our mission of "driving a high-quality life through biotechnology." We will continue to uphold our core values of customer-centricity, striving for professional excellence and outstanding service. Our proposition is to become a leading global enterprise in the development and industrial application of ceramides and other active compounds.

—— Zhihe Bio President & Founder Mr. Dan Yanchun

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Our Journey

Chongqing Zhihe Bio-Pharmaceutical Co.,Ltd. is pioneering the development and industrialization of ceramide-based active compounds worldwide. We create ceramide aesthetic.

Derived from natural and green synthetic biology technology, Zhihe Bio features a fully integrated solution chain from strain construction to ingredient production to formulation application, establishing key differentiation.

Balancing future trends with sustainability, Zhihe Bio is dedicated to the ceramides research, offers safe and comprehensive solutions to ceramides application, enhancing natural beauty pursuit. Zhihe Bio will be your strong partnership to co-create industry prosperity.

2015
Established in Chongqing, China
2021
Started marketization
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2018
Started independently R&D
2023
Started industrialize Established south China and Shanghai batch
2024
Explore the international market

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R&D Milestones

2016
From the original strain of tetraacetyl phytosphingosine, utilized bioinformatics analysis and high-throughput screening breeding technology, gained high-quality candidate strain
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2018
Succeeded in the culture and selection of strain with commercial capacity and process development
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2019
Completed pilot to scaled-up manufacturing and production process validation
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2020
Took the lead in China’s massive production and commenced sales of phytosphingosine and ceramides powder
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2021
Innovated industrial production technology of dihydrosphingosine, being the second enterprise mastering the core technology of this product and achieving large-scale massive production
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2022
Pioneered the industrial production technology of ceramide EOP, achieved the local production of high-end ceramide in China
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2023
Created oil-soluble composite Ceramide solvent, addressed application challenges and acquired national invention patents
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2024
Integrating resources from top experts for years we lauched Liquid Crystal Bionic Ceramide, inaugurating a new era of skincare
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Honours

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Advanced-Team

Yang MAO
Chief Scientist of Synthetic Biology
Yazhuo Shang
Chief Applied Technology Scientist
Hongtao LI
Professor
Wei WU
Professor
Wei You
Chief Synthetic Biology Scientist
Zhiwei Zhang
Chief Cosmetic Formulator
Richard Yang
Marketing General Manager
Congming Zhang
Executive Assistant
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