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Phytosphingosine

Phytosphingosine

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Information
INCI Name Phytosphingosine
CAS No.  554-62-1
AppearanceWhite or off-white powder
Purity≥90.0%(By HPLC-CAD)
Recommended Dosage0.1-2.0%
Structural Formula资源 1@3x.png
SourceYeast fermentation
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Description
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Phytosphingosine is a precursor of ceramide and is one of the important lipid components in the human epidermis. With a structure similar to the content of the stratum corneum, it quickly penetrates into the skin and combines with the water in the stratum corneum to form a net structure that retains moisture. It naturally has the function of repairing the barrier, and also has soothing, calming, desensitizing and anti-allergic effects. It deeply repairs and maintains sensitive skin, enhances skin defense capabilities, and inhibits the reproduction of a variety of harmful bacteria.

Phytosphingosine has two major applications in cosmetics. On one hand, as a key precursor for ceramide, it synthesizes and derives active ingredients such as ceramide NP, AP, and EOP that are widely used in formulas; on the other hand, it also has anti-allergic, soothing, antibacterial and other effects as an active ingredient.

Zhihe Bio applies a synthetic biology technology platform to realize the first tonnage mass production of this product in China. The product features simple production process, green environmental protection, high quality and competitive price, bacterial strains with high yield capacity, modern production process, and stable supply chain, which has proposed a Chinese solution for domestic substitution of high-end active raw materials, and has played a positive role in promoting this product and a series of phytosphingosine-derived products in the personal care industry.

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Product Applications

1. Application areas: 

Many downstream companies purchase phytosphingosine to produce derivative products such as Ceramide NP, AP, and EOP, or directly use it in the compounding of some cosmetic active ingredients.

2. Market performance: 

As the first domestic mass-produced phytosphingosine manufacturer, Zhihe Bio attracted great attention from the industry when launching this product. Based on its application scenarios, this product has excellent production performance and provides domestic substitutions for many domestic companies.

3. Compatibility and solubility: 

Phytosphingosine has poor water solubility and fat solubility, but when using liposome encapsulation/liquid crystal insertion and other delivery technologies, it can be compounded with most cosmetic formulas.

4. Stability: 

This product has good chemical stability. Attention should be paid to its precipitation and stratification in formula concerning material stability. This product has high bioavailability if delivery technology is applied.

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